Theory some may have already heard
I’ve looked through briefly and didn’t see it mentioned but has anyone explored the Grayanotoxin theory?
In The Reichenbach Fall when examining the footprints they found traces of plant matter which was identified as Rhododendron Ponticum. I found something VERY interesting on the matter. In the text, Switzerland as Describes by Great Writers, Reichenbach Falls are described as having very little vegetation it says, “Vegetation seems annihilated, except in the form of rhododendrons, mosses, and lichens.” RHODODENDRONS! The rhododendron contains high levels of Grayanotoxin in both the leaves and the nectar it produces. Symtoms of Grayanotoxin poisoning are as follows:
- Clinical signs generally appear within 6 hours of ingestion.
- Acute digestive upset, salivation, nasal discharge, epiphora.
- Anorexia, depression, nausea, projectile vomiting, frequent defecation, repeated attempts to swallow.
- Weakness, incoordination, paralysis of the limbs, stupor, depression of the heart and central nervous system.
- Aspiration of vomitus is common in ruminants and results in dyspnea and often death.
- Pupillary reflexes may be absent.
- Coma precedes death.
- Animals may remain sick for more than 2 days and gradually recover.
the big ones are EPIPHORA, depression of the heart and nervous system, and lack of pupillary reflex
epiphora is and overflowing of the tear ducts…
SHERLOCK CRIED! (SUPER OUT OF CHARACTER
depression of heart and nervous system means his heart rate would have slowed to practically nothing and his nervous system would stop working
John took his pulse and he “didn’t have one”
Pupils are non-reactive is obviously a big sign of lack of brain function making him look dead.
Right before he meets Moriarty Molly asks if he needs anything he talks to her alone and we don’t see the conversation. We can assume they were discussing the affects of the poison and if he would recover which he would have within 24 hours:
The grayanotoxins bind to sodium channels in cell membranes. The binding unit is the group II receptor site, localized on a region of the sodium channel that is involved in the voltage-dependent activation and inactivation. These compounds prevent inactivation; thus, excitable cells (nerve and muscle) are maintained in a state of depolarization, during which entry of calcium into the cells may be facilitated. This action is similar to that exerted by the alkaloids of veratrum and aconite. All of the observed responses of skeletal and heart muscles, nerves, and the central nervous system are related to the membrane effects.
Because the intoxication is rarely fatal and recovery generally occurs within 24 hours, intervention may not be required. Severe low blood pressure usually responds to the administration of fluids and correction of bradycardia; therapy with vasopressors (agents that stimulate contraction of the muscular tissue of the capillaries and arteries) is only rarely required. Sinus bradycardia and conduction defects usually respond to atropine therapy; however, in at least one instance the use of a temporary pacemaker was required.
I can’t say much on the theory of HOW he survived the fall BUT this does establish a theory on how he tricked John (a trained Dr. into thinking he was dead!)
Sorry again if someone has mentioned this theory previously!